1. Progressive optic atrophy may result in decreased visual acuity or color vision. 2. Visual examination shows optic atrophy and an increase in the blind spot. 3. In some cases, Dominant optic atrophy may remain subclinical until early adulthood. 4. Progression of dominant optic atrophy varies even within the same family. 5. Other ocular defects including optic atrophy , microphthalmia, vitreitis, leukokoria and cataracts can also be seen. 6. It consists of diabetes insipidus, diabetes mellitus, optic atrophy , and deafness, hence the acronym DIDMOAD. 7. Nanri suffered a sudden onset of optic atrophy in 1953 and nearly lost his sight. 8. Neurological symptoms of BVVL include optic atrophy , cerebellar ataxia, retinitis pigmentosa, epilepsy and autonomic dysfunction. 9. This typically evolves to very severe optic atrophy and a permanent decrease of visual acuity. 10. Optic atrophy occurs in the first year and the following symptoms show up before thirteen years.
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